Thermo Fisher Scientific LIN7 Polyclonal Antibody
LIN7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC에 적합합니다. Human, Mouse, Rat 반응성을 가지며, 내부 합성 펩타이드 항원을 기반으로 제작되었습니다. 연구용으로 사용되며 안정적 장기 보관이 가능합니다.
- 카탈로그번호
- OSL00017W-100UL
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific LIN7 Polyclonal Antibody
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:1,000–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from internal region of human LIN7 (A, B, C) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: LIN7A, LIN7B, LIN7C.
Target Information
LIN7A plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
It forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains.
The tripartite complex composed of LIN7 (LIN7A, LIN7B, LIN7C), CASK and APBA1 may couple synaptic vesicle exocytosis to cell adhesion in the brain.
Ensures proper localization of GRIN2B (subunit 2B of NMDA receptor) to neuronal postsynaptic density and may localize synaptic vesicles at synapses via beta-catenin and cadherin.
Required to localize Kir2 channels, GABA transporter (SLC6A12), and EGFR/ERBB family receptors to the basolateral membrane of epithelial cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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