Thermo Fisher Scientific RARRES2 Monoclonal Antibody (4B12)
RARRES2 단클론 항체(4B12)는 인간 RARRES2 단백질을 인식하며 Western blot 및 ELISA에 적합합니다. 마우스 IgG2a, kappa 형이며 비결합 상태로 제공됩니다. 고순도 친화성 크로마토그래피 정제, PBS(pH 7.4) 용액에 보존제 없이 -20°C에 보관합니다.
- 카탈로그번호
- H00005919-M27
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4B12 |
| Immunogen | RARRES2 (NP_002880.1, 17–163 a.a) full-length recombinant protein with GST tag (MW of GST tag = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
VGVAELTEAQ RRGLQVALEE FHKHPPVQWA FQETSVESAV DTPFPAGIFV RLEFKLQQTS CRKRDWKKPE CKVRPNGRKR KCLACIKLGS EDKVLGRLVH CPIETQVLRE AEEHQETQCL RVQRAGEDPH SFYFPGQFAF SKALPRS
Target Information
Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs).
Tazarotene-induced gene (TIG) proteins, also known as retinoic acid receptor responder proteins (RAR-responsive proteins), can be membrane-bound or secreted.
TIGs function as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles, endothelial cells, pancreas, spleen, and intestine.
TIG2 is a secreted protein mainly expressed in epidermis, hair follicles, and endothelial cells. It is inhibited in psoriatic lesions and activated by tazarotene in skin rafts and epidermis of psoriatic lesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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