Thermo Fisher Scientific GABRA4 Polyclonal Antibody
Thermo Fisher Scientific의 GABRA4 Polyclonal Antibody는 Rat 시료에서 반응하며, Western blot 및 ELISA에 사용 가능합니다. Rabbit IgG 기반의 비결합 액상 항체로, 높은 순도(affinity chromatography 정제)와 안정적인 저장 조건을 제공합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 36–258 of human GABRA4 (NP_000800.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.44 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855163 |
Product Specific Information
Immunogen sequence:
QNQKEEKLCT ENFTRILDSL LDGYDNRLRP GFGGPVTEVK TDIYVTSFGP VSDVEMEYTM DVFFRQTWID KRLKYDGPIE ILRLNNMMVT KVWTPDTFFR NGKKSVSHNM TAPNKLFRIM RNGTILYTMR LTISAECPMR LVDFPMDGHA CPLKFGSYAY PKSEMIYTWT KGPEKSVEVP KESSSLVQYD LIGQTVSSET IKSITGEYIV MTVYFHLRRK MGY
Target Information
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain, acting at GABA-A receptors—ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines.
At least 16 distinct subunits of GABA-A receptors have been identified. The GABRA4 gene encodes the alpha-4 subunit, which is implicated in autism risk through interaction with the GABA receptor beta-1 subunit. Alternatively spliced transcript variants encoding different isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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