Thermo Fisher Scientific GABRA4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 36-258 of human GABRA4 (NP_000800.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GABRA4,uniProtId:P48169-1,ncbiNodeId:9606,antigenRange:36-258,antigenLength:554,antigenImageFileName:PA5-109752_GABRA4_P48169-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109752_GABRA4_P48169-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.44 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855163

Product Specific Information

Immunogen sequence: QNQKEEKLCT ENFTRILDSL LDGYDNRLRP GFGGPVTEVK TDIYVTSFGP VSDVEMEYTM DVFFRQTWID KRLKYDGPIE ILRLNNMMVT KVWTPDTFFR NGKKSVSHNM TAPNKLFRIM RNGTILYTMR LTISAECPMR LVDFPMDGHA CPLKFGSYAY PKSEMIYTWT KGPEKSVEVP KESSSLVQYD LIGQTVSSET IKSITGEYIV MTVYFHLRRK MGY

Target Information

Gamma-aminobutyric acid is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1. Alternatively spliced transcript variants encoding different isoforms have been found in this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.