Thermo Fisher Scientific GALC Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human GALC (NP_000144.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GALC,uniProtId:P54803-1,ncbiNodeId:9606,antigenRange:40-300,antigenLength:685,antigenImageFileName:PA5-109753_GALC_P54803-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109753_GALC_P54803-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855164

Product Specific Information

Immunogen sequence: GGAYVLDDSD GLGREFDGIG AVSGGGATSR LLVNYPEPYR SQILDYLFKP NFGASLHILK VEIGGDGQTT DGTEPSHMHY ALDENYFRGY EWWLMKEAKK RNPNITLIGL PWSFPGWLGK GFDWPYVNLQ LTAYYVVTWI VGAKRYHDLD IDYIGIWNER SYNANYIKIL RKMLNYQGLQ RVKIIASDNL WESISASMLL DAELFKVVDV IGAHYPGTHS AKDAKLTGKK LWSSEDFSTL NSDMGAGCWG RILNQNYING Y

Target Information

This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.