Thermo Fisher Scientific SPNS1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SPNS1. Recombinant protein control fragment (Product # if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SPNS1,uniProtId:Q9H2V7-1,ncbiNodeId:9606,antigenRange:1-58,antigenLength:528,antigenImageFileName:PA5-59813_SPNS1_Q9H2V7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-59813_SPNS1_Q9H2V7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647873

Product Specific Information

Immunogen sequence: MAGSDTAPFL SQADDPDDGP VPGTPGLPGS TGNPKSEEPE VPDQEGLQRI TGLSPGRS

Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 84%.

Target Information

SPINSTER, also known as SPNS1 or SPIN1, is a 528 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and belongs to the spinster subfamily of the major facilitator superfamily. SPINSTER interacts with Bcl-x and Bcl-2 and, via this interaction, is thought to be involved in necrotic or autophagic cell death. The related protein SPNS2 is critical for the normal lymphocyte localization and mammalian immune system function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.