Thermo Fisher Scientific FAM111A Polyclonal Antibody
FAM111A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 Human, Mouse, Rat 반응성. 높은 순도(>95%)로 항원 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
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Thermo Fisher Scientific FAM111A Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human FAM111A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718895 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen, and the purity is >95% (by SDS-PAGE).
Target Information
Chromosome 11 comprises approximately 135 million base pairs and 1,400 genes, accounting for about 4% of human genomic DNA. It is considered a gene- and disease-association dense chromosome.
The chromosome 11 encoded Atm gene regulates cell cycle arrest and apoptosis following double-strand DNA breaks; mutations lead to ataxia telangiectasia.
Blood disorders such as sickle cell anemia and β-thalassemia arise from HBB gene mutations.
Wilms' tumors, WAGR syndrome, and Denys-Drash syndrome are linked to WT1 gene mutations.
Other disorders associated with chromosome 11 defects include Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz syndrome.
The FAM111A gene product has been provisionally designated FAM111A pending further characterization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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