Thermo Fisher Scientific FAM111A Polyclonal Antibody

Thermo Fisher Scientific FAM111A Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:1,000

Product Specifications

Product Specific Information

The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen, and the purity is >95% (by SDS-PAGE).

Target Information

Chromosome 11 comprises approximately 135 million base pairs and 1,400 genes, accounting for about 4% of human genomic DNA. It is considered a gene- and disease-association dense chromosome.
The chromosome 11 encoded Atm gene regulates cell cycle arrest and apoptosis following double-strand DNA breaks; mutations lead to ataxia telangiectasia.
Blood disorders such as sickle cell anemia and β-thalassemia arise from HBB gene mutations.
Wilms' tumors, WAGR syndrome, and Denys-Drash syndrome are linked to WT1 gene mutations.
Other disorders associated with chromosome 11 defects include Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz syndrome.
The FAM111A gene product has been provisionally designated FAM111A pending further characterization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.