Thermo Fisher Scientific GTF2A1L Monoclonal Antibody (OTI4B4), TrueMAB
인간 GTF2A1L 단백질(aa 183-478)에 특이적인 단클론 항체로, Western blot에 최적화됨. Mouse IgG1 형식의 비결합 항체이며, 동결건조 형태로 제공. PBS(8% 트레할로스) 버퍼에 보존되며 -20°C에서 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 183–478 of human GTF2A1L produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA.
This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that stabilizes TBP-DNA binding and may play an important role in testis biology.
Alternative splicing generates two isoforms. A rare co-transcribed transcript (SALF) encodes a fusion protein combining sequences from both this gene and its upstream neighbor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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