Thermo Fisher Scientific TRPV4 Polyclonal Antibody
Human TRPV4 단백질을 표적으로 하는 Rabbit Polyclonal Antibody. IHC(P)에서 2.5–5 µg/mL로 사용 가능. Antigen affinity chromatography로 정제된 액상 시약. 4°C 단기, -20°C 장기 보관. 연구용으로만 사용.
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Thermo Fisher Scientific TRPV4 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 2.5–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from N-terminus of human TRPV4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.91 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551643 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human (100%)
- Marmoset (94%)
- Panda, Dog (89%)
- Hamster, Bovine, Pig (83%)
Target Information
TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) is a cation-selective channel activated in response to systemic osmotic pressure. It is a non-selective calcium permeant cation channel involved in osmotic sensitivity and mechanosensitivity. TRPV4 belongs to the OSM9-like transient receptor potential channel (OTRPC) subfamily within the TRP superfamily of ion channels.
Mutations in the TRPV4 gene cause spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC.
Diseases associated with TRPV4 include Metatropic Dysplasia and Spondylometaphyseal Dysplasia, Kozlowski Type. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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