Thermo Fisher Scientific CD263 (TRAIL-R3) Polyclonal Antibody
인간 CD263(TRAIL-R3)을 인식하는 Rabbit Polyclonal Antibody. Western blot 및 ELISA에 사용 가능. TRAIL 유도 세포사멸 억제 연구에 적합. 비결합형 액상 형태로 제공되며 4°C 또는 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Rabbit Polyclonal to TRAIL - Receptor 3 (TRAIL-R3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_561791 |
Product Specific Information
PA1-23498 detects TRAIL-Receptor 3 in human samples.
Target Information
TRAIL-R3 (CD263) is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. It cannot induce apoptosis and functions as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene is a p53-regulated, DNA damage-inducible gene, expressed in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to TRAIL-induced apoptosis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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