Thermo Fisher Scientific P2X7 Polyclonal Antibody
Human P2X7 수용체를 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:50–1:200 희석으로 사용 가능. Antigen affinity chromatography로 정제되었으며 PBS/glycerol buffer에 보관. ATP 의존성 이온 채널 연구에 적합.
- 카탈로그번호
- PA559823
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human C12orf76. Recombinant protein control fragment (Product #RP-98949) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2638741 |
Product Specific Information
Immunogen sequence:
AEVKEEIVEK EMKKLVHSVF NMADYTFPLQ
Antigen sequence identity:
- Mouse: 60%
- Rat: 57%
Target Information
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and mediates ATP-dependent lysis of macrophages through formation of membrane pores permeable to large molecules. Activation of this receptor by ATP in the cytoplasm may couple cellular activity to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay criteria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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