Thermo Fisher Scientific DOK3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human DOK3 protein. Validated for Western blot applications with 1:500–1:3,000 dilution range. Antigen affinity purified and supplied as a 1 mg/mL liquid in Tris-glycine buffer. For research use only.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 434–496 of DOK3 (Uniprot ID: Q7L591) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_11156180 |
Product Specific Information
- Recommended positive control: A431
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
DOK3 proteins act as adaptor or scaffolding proteins, providing docking platforms for multimolecular signaling complexes. DOK3 negatively regulates JNK signaling in B-cells via interaction with INPP5D/SHIP1 and may modulate ABL1 function.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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