Thermo Fisher Scientific FANCE Polyclonal Antibody
FANCE 단백질을 인식하는 Thermo Fisher의 rabbit polyclonal 항체로, Western blot 및 Immunocytochemistry에 사용 가능. Human 시료 반응성. Affinity chromatography로 정제되었으며, 0.1 mg/mL 농도의 액상 형태로 제공. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 112–252). Recombinant protein control fragment (Product # RP-110203) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091728 |
Product Specific Information
Immunogen sequence:
SGLLSVLQIA QQDLAPDPDA WLRALGELLR RDLGVGTSME GASPLSERCQ RQLQSLCRGL GLGGRRLKSP QAPDPEEEEN RDSQQPGKRR KDSEEEAASP EGKRVPKRLR CWEEEEDHEK ERPEHKSLES LADGGSASPI K
Antigen sequence identity:
Mouse 27%; Rat 51%
Target Information
The Fanconi anemia complementation group (FANC) includes FANCA, FANCB, FANCC, FANCD1 (BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (BRIP1), FANCL, FANCM, and FANCN (PALB2).
Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair.
The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex.
This gene encodes the protein for complementation group E (FANCE).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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