Thermo Fisher Scientific MEF2C Polyclonal Antibody
MEF2C 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, ELISA 등에 적합하며 인간 및 마우스 반응성. 고순도 Affinity Chromatography 정제, 3.97 mg/mL 농도, PBS/glycerol buffer에 보관.
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Thermo Fisher Scientific MEF2C Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 170–380 of human MEF2C (NP_0023882) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.97 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913728 |
Product Specific Information
- Positive test controls: Mouse brain
- Localization: Nucleus
Immunogen sequence:
LPLAHPSLQR NSMSPGVTHR PPSAGNTGGL MGGDLTSGAG TSAGNGYGNP RNSPGLLVSP GNLNKNMQAK SPPPMNLGMN NRKPDLRVLI PPGSKNTMPS VSEDVDLLLN QRINNSQSAQ SLATPVVSVA TPTLPGQGMG GYPSAISTTY GTEYSLSSAD LSSLSGFNTA SALHLGSVTG WQQQHLHNMP PSALSQLGAC TSTHLSQSSN L
Target Information
MEF2C is a transcription activator that binds specifically to the MEF2 element found in the regulatory regions of many muscle-specific genes. It controls cardiac morphogenesis, myogenesis, and vascular development. MEF2C plays a key role in hippocampal-dependent learning and memory by regulating synaptic transmission. It is crucial for normal neuronal development, cortical architecture, megakaryocyte and platelet formation, and B-cell development and survival. Isoforms lacking the repressor domain are more active than those containing it.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: PA5-120156_MEF2C_Q06413-1_Rabbit.svg, PA5-120156_MEF2C_Q06413-1_Rabbit_PDP.jpeg)
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