Thermo Fisher Scientific COL7A1 Polyclonal Antibody
Rabbit polyclonal antibody against human COL7A1 for IHC (paraffin) applications. Recognizes type VII collagen alpha chain. Supplied as liquid, 0.6 mg/mL concentration. For research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human COL7A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790763 |
Product Specific Information
Immunogen sequence:
LTLYTLLEGH EVATPATVVP TGPELPVSPV TDLQATELPG QRVRVSWSPV PGATQYRIIV RSTQGVERTL VLPGSQTAFD LDDVQAGLSY TVRVSARVGP REGSASVLTV RREPETPLAV PGLRVVVSDA TRVRVAWGPA PGASGFRI
Target Information
This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.
[provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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