Thermo Fisher Scientific PGAM1 Polyclonal Antibody
Thermo Fisher Scientific의 PGAM1 Polyclonal Antibody는 인간 PGAM1 단백질을 인식하는 토끼 유래 IgG 항체로, WB, IHC, ICC/IF에 사용 가능합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS/40% 글리세롤 용액 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PGAM1. Recombinant protein control fragment (Product #RP-104342). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790770 |
Product Specific Information
Immunogen sequence: PPMEPDHPFY SNISKDRRYA DLTEDQLPS
Target Information
PGAM1 belongs to the phosphoglycerate mutase family. It plays a key role in glucose and 2,3-BPGA metabolism, catalyzing the reversible conversion of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway.
PGAM1 is a dimeric enzyme composed of muscle (MM), brain (BB), and hybrid (MB) isozymes in different tissues.
Mutations in PGAM1 cause muscle phosphoglycerate mutase deficiency (glycogen storage disease X).
Recombinant human PGAM protein, fused to a His-tag at the N-terminus, was expressed in E. coli and purified using conventional chromatography techniques.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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