Thermo Fisher Scientific gamma Actin Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000
• Recommended positive control: NIH-3T3

Predicted Reactivity

• Mouse (100%)
• Rat (100%)
• Xenopus laevis (100%)
• Dog (100%)
• Chicken (99%)
• Chimpanzee (100%)
• Bovine (100%)

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Product Specifications

Target Information

Actins are highly conserved proteins involved in various types of cell motility and cytoskeletal maintenance.
Three main groups of actin isoforms are identified in vertebrates: alpha, beta, and gamma.

• Alpha actins: Found in muscle tissues; major component of the contractile apparatus.
• Beta and gamma actins: Present in most cell types; components of the cytoskeleton and mediators of internal cell motility.

Actin gamma 1, encoded by this gene, is a cytoplasmic actin found in all cell types.
Mutations are associated with DFNA20/26 (autosomal dominant sensorineural progressive hearing loss) and Baraitser-Winter syndrome.
Alternative splicing results in multiple transcript variants.

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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