Thermo Fisher Scientific POU6F1 Polyclonal Antibody, MaxPab
POU6F1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화된 연구용 시약으로 인간 시료 반응성. Affinity chromatography로 정제된 액상 형태이며, PBS buffer에 보존제 없이 -20°C 보관.
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Applications
- Western Blot (WB): 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | POU6F1 (AAH74765.3, 1–301 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MPGISSQILT NAQGQVIGTL PWVVNSASVA APAPAQSLQV QAVTPQLLLN AQGQVIATLA SSPLPPPVAV RKPSTPESPA KSEVQPIQPT PTVPQPAVVI ASPAPAAKPS ASAPIPITCS ETPTVSQLVS KPHTPSLDED GINLEEIREF AKNFKIRRLS LGLTQTQVGQ ALTATEGPAY SQSAICRFEK LDITPKSAQK LKPVLEKWLN EAELRNQEGQ QNLMEFVGGE PSKKRKRRTS FTPQAIEALN AYFEKNPLPT GQEITEIAKE LNYDREVVRV WFCNRRQTLK NTSKLNVFQI P
Target Information
Brn-5 (Brain-5), also known as POU6F1, MPOU or TCFB1, is a widely expressed protein but during embryogenesis is exclusively found in the developing brain and spinal cord.
It contains two DNA-binding domains — the POU-specific domain and the POU homeodomain — each with an HTH (helix-turn-helix) motif.
Brn-5 binds to CRH (corticotrophin-releasing hormone) elements with high affinity and can enhance Prolactin gene expression and activate Pit-1 expression.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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