
Thermo Fisher Scientific STX1A/STX1B Polyclonal Antibody
Rabbit polyclonal antibody recognizing Syntaxin-1A/1B for WB and IHC applications. Suitable for neuroscience research on synaptic vesicle docking and ion channel regulation. Lyophilized form; reconstitute with distilled water; storage at 4°C or -20°C.
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Applications
- Western Blot (WB): 1:300–1:2,000
- Immunohistochemistry (IHC): 1:300–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 60–110 of mouse Syntaxin-1A conjugated to blue carrier protein; homologous in rat and human |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2199684 |
Product Specific Information
Reconstitute with 100 µL of distilled water.
Target Information
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins involved in synaptic vesicle docking with the presynaptic plasma membrane. They possess a single C-terminal transmembrane domain, a SNARE domain, and an N-terminal regulatory domain. Syntaxins bind synaptotagmin in a calcium-dependent manner and interact with voltage-dependent calcium and potassium channels via the C-terminal H3 domain. This gene product plays a key role in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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