Thermo Fisher Scientific FOG1/ZFPM1 Polyclonal Antibody
FOG1/ZFPM1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC 및 IHC(P) 실험에 사용 가능. Human에 반응하며, Gorilla 및 Chimpanzee에도 예측 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로 4°C에서 보관.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 175 and 225 of human friend of GATA-1 (zinc finger protein, multitype 1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Gorilla and Chimpanzee
Target Information
ZFPM1 is a transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation.
It acts as an essential cofactor forming heterodimers with GATA family transcription factors (GATA1, GATA2, GATA3).
These heterodimers can activate or repress transcription depending on cellular and promoter context.
They activate genes such as NFE2, ITGA2B, α- and β-globin, and repress KLF1 expression.
ZFPM1 may also regulate genes in gonads and contribute to cardiac development in cooperation with ZFPM2/FOG2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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