Thermo Fisher Scientific GLP-1 Monoclonal Antibody (53)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

53

Immunogen

Synthetic GLP-1(9-18) adsorbed onto aluminum hydroxide gel. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GLP-1,uniProtId:P01275-1,ncbiNodeId:9606,antigenRange:9-18,antigenLength:180,antigenImageFileName:ABS_044-53-02_GLP-1_P01275-1_House_mouse.svg,antigenImageFileNamePDP:ABS_044-53-02_GLP-1_P01275-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.15 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

15mM sodium azide

Storage conditions

4° C, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2536222

Product Specific Information

Specificity: ABS 044-53-02 binds human GLP-1 (9-36) amide. Based on inhibition ELISA, this antibody shows less than 2% cross-Specificity with GLP-1 (7-36) amide.

Reactivity: ABS 044-53-02 binds free GLP-1 (9-36) amide in solution. This product has a higher affinity for GLP-1 (9-36) amide than ABS 044-49-02 as determined by an Inhibition assay.

NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL

Target Information

GCG is also known as GLP1, or Glucagon. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis.It is mapped to 2q36-2q37. GLP1, also known as 7-37 for the codons of the preproglucagon molecule which encode it, renders pancreatic beta-cells glucose-competent and may be useful in the treatment of noninsulin-dependent diabetes mellitus. Also, GLP1 is a potent insulin secretagogue.It plays a major role in the enteroinsular axis, accounting, for example, for the finding that plasma insulin levels accompanying oral intake of glucose are greater than those observed when glucose is given intravenously.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.