
Thermo Fisher Scientific OSGEP Monoclonal Antibody (OTI8B3), TrueMAB
Human OSGEP 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, WB, IHC(P), ICC/IF에 적합. Affinity chromatography로 정제된 액상 제품이며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8B3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–335 of human OSGEP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.58 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Osgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that belongs to the peptidase M22 family.
Osgep specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but does not cleave desialylated glycoproteins, unglycosylated proteins, or glycoproteins that are only N-glycosylated.
It is ubiquitously expressed at low levels, with highest expression in liver, skeletal muscle, and kidney.
OSGEPL1 (Qri7), a related 414 amino acid protein, belongs to the KAE1/YgjD family and exists as three alternatively spliced isoforms.
In tRNAs with codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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