Thermo Fisher Scientific RBBP6 Polyclonal Antibody
RBBP6 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 사용 가능. Human 및 Mouse 시료에 반응하며, Affinity chromatography로 정제된 1 mg/mL 액상 제품. PBS buffer(50% glycerol)로 안정화되어 -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RBBP6 (Accession Q7Z6E9), corresponding to amino acid residues F1440–E1490 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853428 |
Product Specific Information
Antibody detects endogenous levels of total RBBP6.
Target Information
This gene encodes a cilia-associated protein belonging to the kinesin family. It plays a role in the sonic hedgehog (SHH) signaling pathway through regulation of GLI transcription factors. It acts as a negative regulator by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by inhibiting the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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