Thermo Fisher Scientific COX5B Polyclonal Antibody
COX5B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, IP 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. 고순도 항원 친화 크로마토그래피 정제. 연구용 전용 제품.
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Thermo Fisher Scientific COX5B Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1:50–1:100 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human COX5B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803718 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
The cytochrome c oxidase (COX) family of proteins functions as the final electron donor in the respiratory chain, driving a proton gradient across the inner mitochondrial membrane and resulting in water production.
The mammalian COX apoenzyme is a dimer composed of 13 subunits, both mitochondrial and nuclear.
COX5 is located in the inner mitochondrial membrane and is the heme A-containing chain of the oxidase family that converts one molecule of oxygen and four molecules of hydrogen to two molecules of water.
Two isoforms, COX5a and COX5b, exist. COX5a is up-regulated under high oxygen (aerobic) conditions, while COX5b is up-regulated under low oxygen (hypoxic) conditions to optimize COX turnover.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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