Thermo Fisher Scientific AKT3 (E17K Mutant) Polyclonal Antibody
AKT3 (E17K Mutant) 특이적 폴리클로날 항체로 Western blot에 최적화됨. 인간 반응성, 토끼 IgG 호스트. 액상 형태, 항원 친화 크로마토그래피로 정제. 세포 신호 조절 연구 및 변이 단백질 검출에 적합.
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Thermo Fisher Scientific AKT3 (E17K Mutant) Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human AKT3 (E17K Mutant Specific). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2735442 |
Product Specific Information
- Positive Control: Akt3(E17K)-transfected 293T cells
- Predicted Reactivity: Mouse (100%), Pig (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by AKT3 (E17K Mutant Specific) belongs to the AKT (PKB) serine/threonine kinase family, which regulates cell signaling in response to insulin and growth factors.
AKT kinases are involved in processes such as:
- Cell proliferation and differentiation
- Apoptosis and tumorigenesis
- Glycogen synthesis and glucose uptake
This kinase is stimulated by PDGF, insulin, and IGF1.
Alternative splice variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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