Thermo Fisher Scientific MYOZ2 Polyclonal Antibody
MYOZ2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot, ICC/IF, ELISA에 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제, PBS/glycerol buffer에 보관. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein corresponding to amino acids 1–264 of human MYOZ2 (NP_057683.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806580 |
Product Specific Information
Immunogen sequence:
MLSHNTMMKQ RKQQATAIMK EVHGNDVDGM DLGKKVSIPR DIMLEELSHL SNRGARLFKM RQRRSDKYTF ENFQYQSRAQ INHSIAMQNG KVDGSNLEGG SQQAPLTPPN TPDPRSPPNP DNIAPGYSGP LKEIPPEKFN TTAVPKYYQS PWEQAISNDP ELLEALYPKL FKPEGKAELP DYRSFNRVAT PFGGFEKASR MVKFKVPDFE LLLLTDPRFM SFVNPLSGRR SFNRTPKGWI SENIPIVITT EPTDDTTVPE SEDL
Positive Samples: Mouse heart, Mouse skeletal muscle, Rat skeletal muscle
Cellular Location: Cytoplasm, Z line, myofibril, sarcomere
Target Information
The calcineurin-binding protein Myozenin 2 (calsarcin-1) is a member of the calsarcin protein family. Calcineurin is a calcium- and calmodulin-dependent protein phosphatase involved in regulating slow fiber gene expression in skeletal muscle and cardiac muscle hypertrophy. Calsarcins are sarcomeric proteins that link calcineurin to muscle activity. In cardiac and skeletal muscle, Myozenin 2 binds calcineurin to α-actinin at the Z-line of the sarcomere. During embryogenesis, Myozenin 1 and 2 are expressed in developing muscle. Myozenin 2 is expressed in adult cardiac and slow-twitch skeletal muscle, while Myozenin 1 is found in fast skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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