Thermo Fisher Scientific Cell division control protein septin D1 Polyclonal Antibody
Cell division control protein septin D1에 특이적인 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human MSF/Cell division control protein septin D1, amino acids 351–450 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB, and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucine zipper motifs, which allow homodimerization as well as heterodimerization with other bZip transcription factors. Large Mafs contain an acidic transactivation domain absent in small Maf proteins. Although small Maf proteins lack inherent transactivation activity, they can act as positive regulators of transcription by partnering with transcriptionally active dimerization partners, or as negative regulators by recruiting repressors or forming inactive homodimers. Human MafF encodes a 164 amino acid protein with an extended leucine zipper structure and no N-terminal transactivation domain. Small Maf proteins are involved in development, differentiation, hematopoiesis, and stress response, each regulating stress mechanisms differently.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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