Thermo Fisher Scientific Transthyretin Polyclonal Antibody
Transthyretin 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC, Flow cytometry에 사용 가능. Human 및 Rat에 반응하며 Protein A 및 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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- PA535315
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25 | - |
| Immunocytochemistry (ICC/IF) | 1:25 | 1 publication |
| Flow Cytometry (Flow) | 1:25 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between 71-98 amino acids from the C-terminal region of human TTR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2552625 |
Product Specific Information
This antibody is predicted to react with non-human primate based on sequence homology.
Target Information
Transthyretin (TTR), also known as prealbumin, is a plasma protein that functions as a transporter of thyroxine and retinol-binding protein. It is primarily produced in the liver and secreted into plasma. TTR constitutes about 25% of CSF protein, suggesting selective transport across the blood-CSF barrier or synthesis within the CNS. Transthyretin is found in neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. Over 40 different mutations in the TTR gene have been associated with amyloid deposition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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