Thermo Fisher Scientific CDKN2B Polyclonal Antibody
Human CDKN2B 단백질을 인식하는 Rabbit Polyclonal 항체. IHC(P)에서 1:50–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제됨. PBS, 40% 글리세롤, 0.02% sodium azide 보존액. 연구용으로 4°C 또는 -20°C 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CDKN2B (Product #RP-103503) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856973 |
Product Specific Information
Immunogen sequence:
MREENKGMPS GGGSDEGLAS AAARGLVEKV RQLLEAG
Target Information
The four known 15–19 kDa INK4 proteins (p15INK4b, p16INK4a, p18INK4c, and p19INK4d) bind and inhibit CDK4 and CDK6 but not other CDKs, including cyclin E-Cdk2, cyclin A-Cdk2, and cyclin B-Cdk1. Like the three D-type cyclins, the INK4 genes are expressed in distinct tissue-specific patterns, suggesting that they are not strictly redundant. p18INK4c is expressed during the G1 to S transition in the eukaryotic cell division cycle and is maximally induced as cells enter S-phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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