Thermo Fisher Scientific MARCKSL1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

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Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MARCKSL1. Recombinant protein control fragment (Product #RP-102571). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MARCKSL1,uniProtId:P49006-1,ncbiNodeId:9606,antigenRange:86-181,antigenLength:195,antigenImageFileName:PA5-56495_MARCKSL1_P49006-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56495_MARCKSL1_P49006-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.20 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643766

Product Specific Information

Immunogen sequence: PKKKKKFSFK KPFKLSGLSF KRNRKEGGGD SSASSPTEEE QEQGEIGACS DEGTAQEGKA AATPESQEPQ AKGAEASAAS EEEAGPQATE PSTPSG

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

Target Information

MARCKS (Myristoylated alanine-rich protein kinase C substrate), also designated 80K or 80K-L, is a 332 amino acid protein that localizes to the plasma membrane and functions as a major cellular substrate for protein kinase C (PKC). MARCKSL1 (MARCKS-like protein 1), also known as MacMARCKS, MLP, MRP, or F52, is a 195 amino acid protein that, like MARCKS, is a major substrate for PKC. Expressed in a variety of tissues with highest levels found in testis and uterus, MARCKSL1 participates in the coordination of membrane-cytoskeletal signaling events, including secretion, migration, phagocytosis and cell adhesion. Additionally, MARCKSL1 functions as a regulator of Integrin activation and is thought to regulate Integrin-dependent signal transduction pathways, especially those involved in macrophage spreading.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.