Thermo Fisher Scientific GPR83 Polyclonal Antibody
GPR83 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunocytochemistry에 사용 가능. A549 및 HCT116 세포에서 양성 대조로 추천되며, 뇌에서 특이적으로 발현되는 GPR83 연구에 적합. 4°C 단기 보관, -20°C 장기 보관 권장.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 359–423 of Human GPR83 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2546245 |
Product Specific Information
- Recommended positive controls: A549, HCT116
- Predicted reactivity: Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
GPR83, a 423 amino acid protein, is an orphan member of the GPCR protein family and is closely related to tachykinin and NPY receptors. It is a human homolog of mouse GIR protein and is exclusively expressed and selectively up-regulated in the brain. It is a cell surface receptor protein consisting of a putative seven-transmembrane domain. Reports suggest GPR83 may be involved in the regulation of immune tolerance mechanisms by inducing peripheral generation of Foxp3+ Treg cells.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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