Thermo Fisher Scientific CXCL6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.1 µg/mL

-

Neutralization (Neu)

0.8-4.0 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

E. coli-derived recombinant human CXCL6/GCP-2 Val40-Asn114 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CXCL6,uniProtId:P80162-1,ncbiNodeId:9606,antigenRange:40-114,antigenLength:114,antigenImageFileName:PA5-46937_CXCL6_P80162-1_Goat.svg,antigenImageFileNamePDP:PA5-46937_CXCL6_P80162-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2608254

Product Specific Information

In direct ELISAs and Western blots, less than 10% cross-reactivity with recombinant mouse (rm) MIP-2, rmKC, rmCXCL6, recombinant human (rh) ENA-78, recombinant rat (rr) CINC-2 alpha, rmCRG-2, rhNAP-2 is observed and less than 5% cross-reactivity with rrCINC-2 beta and rhMCP-3 is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

Endoxin level is <0.20 EU per 1 µg of the antibody by the LAL method.

Target Information

CXCL6 is a chemotactic for neutrophil granulocytes. It signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.