Thermo Fisher Scientific Importin 7 Polyclonal Antibody
Human Importin 7 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF 등 면역세포화학 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 40% 글리세롤 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Importin 7. Recombinant protein control fragment (Product #RP-106714). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856847 |
Product Specific Information
Immunogen Sequence:
NRNPVWYQAL THGLNEEQRK QLQDIATLAD QRRAAHESKM IEKHGGYKFS APVVPSSFNF GGPAPGMN
Target Information
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran’s GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP. It also binds directly to nuclear pore complexes, competing for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and can cross the nuclear envelope rapidly in both directions. At least four importin beta-like transport receptors—importin beta, transportin, RanBP5, and RanBP7—directly bind and import ribosomal proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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