Thermo Fisher Scientific GPR112 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GPR112. Recombinant protein control fragment (Product #RP-94997). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPR112,uniProtId:Q8IZF6-1,ncbiNodeId:9606,antigenRange:2430-2525,antigenLength:3080,antigenImageFileName:PA5-57228_GPR112_Q8IZF6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57228_GPR112_Q8IZF6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642158

Product Specific Information

Immunogen sequence: INTGKSQWEK PKFKQCKLLQ ELPDKIVDLA NITISDENAE DVAEHILNLI NESPALGKEE TKIIVSKISD ISQCDEISMN LTHVMLQIIN VVLEKQ

Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 27%.

Target Information

G protein-coupled receptors(GPRs or GPCRs), also known asseven transmembrane receptors, heptahelical receptors or 7TMreceptors, aremembers of the largest protein family and play a role in many differentstimulus-response pathways. G protein-coupled receptors mediate extracellularsignals into intracellularsignals(G protein activation). Theyrespond to awide variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are usuallyintegralseven passmembrane proteins with some conserved amino acid regions. GPR112 (G protein-coupled receptor 112) is a 3,080 amino acid multi-pass membrane protein that belongsto the G-protein coupled receptor 2 family and LN-TM7 subfamily. Localizing to cell membrane, GPR112 is highly expressed in normal enterochromaffin cells, aswell as neuroendocrine and primarylivercarcinoma. GPR112 contains one GPS domain andmayfunction as an orphan receptor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.