Thermo Fisher Scientific GPR112 Polyclonal Antibody
Human GPR112 단백질에 특이적인 Rabbit Polyclonal Antibody. IHC(P)에서 1:50~1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GPR112. Recombinant protein control fragment (Product # RP-94997) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642158 |
Product Specific Information
Immunogen sequence:
INTGKSQWEK PKFKQCKLLQ ELPDKIVDLA NITISDENAE DVAEHILNLI NESPALGKEE TKIIVSKISD ISQCDEISMN LTHVMLQIIN VVLEKQ
Antigen sequence identity:
- Mouse: 79%
- Rat: 27%
Target Information
G protein-coupled receptors (GPRs or GPCRs), also known as seven transmembrane receptors or 7TM receptors, are members of the largest protein family involved in various stimulus-response pathways. They mediate extracellular signals into intracellular responses through G protein activation and respond to signaling molecules such as hormones, neurotransmitters, and peptides.
GPR112 (G protein-coupled receptor 112) is a 3,080 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and LN-TM7 subfamily. Localized to the cell membrane, GPR112 is highly expressed in normal enterochromaffin cells, as well as in neuroendocrine and primary liver carcinoma. It contains one GPS domain and may function as an orphan receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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