Thermo Fisher Scientific Histone H3 Monoclonal Antibody (3-C4)
Western blot, IHC, ICC/IF에 적합한 Histone H3 단클론 항체. Human, Mouse, Rat에 반응하며 IgG1 아이소타입. Protein A로 정제된 2 mg/mL 액상 형태로, 장기 보관 시 -20°C에서 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1000–1:2000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3-C4 |
| Immunogen | Synthetic peptide within C-terminal residues of human Histone H3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931501 |
Target Information
Histone H3 is a DNA-binding protein found in the chromatin of all eukaryotic cells. Together with four core histone proteins, it binds to DNA to form the nucleosome structure. Histones play a crucial role in transcription regulation, DNA repair, replication, and chromosomal stability. The N-terminal tail of histone H3 can undergo various post-translational modifications, such as methylation, acetylation, and phosphorylation, which influence chromatin structure and gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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