Thermo Fisher Scientific LRRFIP2 Polyclonal Antibody
Thermo Fisher Scientific의 LRRFIP2 Polyclonal Antibody는 인간 및 마우스 반응성을 가진 Rabbit IgG 기반 항체로, Wnt 및 TLR4 신호전달 연구에 적합합니다. IHC(P)에서 1:100~1:1,000 희석으로 사용되며, 항원 친화 크로마토그래피로 정제된 고품질 액상 제품입니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human LRRFIP2 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.27 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2736103 |
Product Specific Information
- Predicted Reactivity: Human (100%), Rat (94%), Xenopus laevis (81%), Bovine (95%)
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The leucine-rich repeat FLI-I-interacting protein 2 (LRRFIP2) is a component of the Wnt signaling pathway, modulating Wnt signaling through interactions with Disheveled to increase cellular levels and transcriptional activity of beta-catenin.
LRRFIP2 also acts as a positive regulator of the TLR4 signaling pathway for activating NF-kappa-B during the early host response to LPS stimulation, through binding to the TLR adaptor protein MyD88. This interaction is governed by phosphorylation of specific residues in LRRFIP2.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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