Thermo Fisher Scientific Phospho-Myt1 (Ser83) Polyclonal Antibody
Phospho-Myt1 (Ser83) 폴리클로날 항체로 인간, 마우스, 랫트 반응성을 보입니다. Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능하며, Protein A로 정제된 고순도 항체입니다. 세포주기 조절 연구에 적합한 연구용 시약입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human Myt1 around phosphorylation site Ser83 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of a family of neural-specific, zinc finger-containing DNA-binding proteins. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), thus negatively regulating the cell cycle G2/M transition. It is associated with the membrane throughout the cell cycle, and its activity is highly regulated. Protein kinases AKT1/PKB and PLK (Polo-like kinase) phosphorylate and regulate this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported. The protein binds to promoter regions of proteolipid proteins in the central nervous system and plays a role in nervous system development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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