Thermo Fisher Scientific CLEC14A Polyclonal Antibody
Thermo Fisher Scientific의 CLEC14A Polyclonal Antibody는 인간 CLEC14A 단백질을 인식하는 토끼 다클론 항체로, ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CLEC14A (Product # RP-106173) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856677 |
Product Specific Information
Immunogen sequence:
RCAVLQATGG VEPAGWKEMR CHLRANGYLC KYQFEVLCPA PRPGAASNLS YRAPFQLHSA ALDFSPPGTE VS
Target Information
CLEC-14A (C-type lectin domain family 14 member A), also known as EGFR-5 or CEG1, is a 490 amino acid single-pass type I membrane protein that contains one C-type lectin domain and an EGF-like domain. The gene encoding CLEC-14A maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, one of the three key genes associated with the development of Alzheimer’s disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder alpha1-antitrypsin deficiency, characterized by severe lung complications and liver dysfunction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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