Thermo Fisher Scientific MRPS22 Polyclonal Antibody
Thermo Fisher Scientific MRPS22 Polyclonal Antibody는 인간, 생쥐, 랫트에서 반응하는 Rabbit IgG 폴리클로날 항체입니다. Western blot, IHC, ICC/IF에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 버퍼에 보관되며 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRPS22. Recombinant protein control fragment (Product #RP-88794). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644189 |
Product Specific Information
Immunogen sequence:
TKKPTFMDEE VQSILTKMTG LNLQKTFKPA IQELKPPTYK LMTQAQLEEA TRQAVEAAKV RLKMPPVLEE RVPINDVLAE DKILEGTETT KYVFTDISYS IPHRERFIVV REPSGTLRKA
Antigen sequence identity:
- Mouse: 91%
- Rat: 93%
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and facilitate protein synthesis within mitochondria. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition—contrary to prokaryotic ribosomes. Mammalian mitoribosomes lack a 5S rRNA. The proteins comprising the mitoribosome vary significantly among species, making sequence homology recognition difficult.
The MRPS22 gene encodes a 28S subunit protein unique to mammalian mitoribosomes, located telomeric and transcribed opposite to the forkhead box L2 gene. A pseudogene corresponding to MRPS22 exists on chromosome Xq.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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