Thermo Fisher Scientific c-Fos Monoclonal Antibody (2G2)
인간 FOS 단백질을 인식하는 Thermo Fisher Scientific의 c-Fos 단클론 항체(2G2). Western blot, IHC, Flow cytometry, ELISA 등 다양한 응용에 적합. 비결합형 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적 유지. 연구용으로만 사용 가능.
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- MA517076
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2G2 |
| Immunogen | Purified recombinant fragment of human FOS expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2538547 |
Product Specific Information
MA5-17076 targets FOS in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human FOS expressed in E. coli.
MA5-17076 detects FOS with a predicted molecular weight of approximately 40.7 kDa.
Target Information
FBJ murine osteosarcoma viral oncogene homolog, commonly known as cellular proto-oncogene Fos (c-Fos), belongs to the Fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14.
c-Fos heterodimerizes with c-Jun to form the Activator Protein-1 (AP-1) transcription factor, which regulates transcription of several genes involved in cellular signal transduction, proliferation, and differentiation.
c-Fos is phosphorylated by various stimuli, including growth factors and insulin, at multiple sites. The upstream kinase ERK MAPK phosphorylates c-Fos at threonine 232, regulating its nuclear localization and transcriptional activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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