Thermo Fisher Scientific SULT2A1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:5,000–1:20,000

Product Specifications

Product Specific Information

• Recommended positive control: HepG2
• Store product as a concentrated solution.
• Centrifuge briefly prior to opening the vial.

Target Information

SULT1 sulfotransferases exhibit N-sulfating activity toward carcinogenic heterocyclic amines and are selective for phenols, whereas SULT2 enzymes prefer hydroxysteroids and SULT3 family members are selective for N-substituted aryl and alicyclic compounds.
SULT2A1 catalyzes the sulfonation of procarcinogen xenobiotics, hydroxysteroids, and bile acids, and is highly expressed in adrenal and liver tissues. It plays a role in hepatic cholesterol homeostasis.
SULT2B1 consists of two isoforms, SULT2B1a and SULT2B1b, transcribed from the same gene by alternative splicing. Both isoforms are selective for the sulfation of 3β-hydroxysteroids such as pregnenolone, epiandrosterone, DHEA, and androstenediol. SULT2B1b is expressed in prostate, skin, placenta, and lung.

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.