Thermo Fisher Scientific IL10RA Monoclonal Antibody (OTI1D10), TrueMAB
IL10RA 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot과 IHC(Paraffin)에 적합. 인간 시료 반응성, 비결합형 액상 형태. 고순도 친화 크로마토그래피 정제, 안정적 PBS/BSA/glycerol 버퍼 구성. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:4,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D10 |
| Immunogen | Full length human recombinant protein of human IL10RA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It mediates the immunosuppressive signal of interleukin 10, inhibiting the synthesis of proinflammatory cytokines.
It promotes survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway.
Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.
Two transcript variants, one protein-coding and the other non-coding, have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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