Thermo Fisher Scientific IL10RA Monoclonal Antibody (OTI1C7), TrueMAB
IL10RA 단백질을 표적으로 하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS/BSA/glycerol 용액 형태로 제공되며 -20°C에서 보관합니다.
- 카탈로그번호
- TA506931
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB)
Tested Dilution
- 1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C7 |
| Immunogen | Full length human recombinant protein of human IL10RA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It mediates the immunosuppressive signal of interleukin 10, inhibiting synthesis of proinflammatory cytokines. The receptor promotes survival of progenitor myeloid cells via the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and one non-coding, have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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