Thermo Fisher Scientific Caspase 1 p20 Recombinant Rabbit Monoclonal Antibody (1N2U7)
Caspase-1 p20 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 시료에 반응하며, 고순도의 액상 형태로 제공됩니다. 면역원은 인간 Caspase-1 p20의 200–300번 아미노산 서열 기반입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:8,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1N2U7 |
| Immunogen | A synthetic peptide corresponding to amino acids 200–300 of human Caspase-1 p20 (NP_001244047.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.27 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_3093076 |
Product Specific Information
Immunogen sequence:
DVKKNLTASD MTTELEAFAH RPEHKTSDST FLVFMSHGIR EGICGKKHSE QVPDILQLNA IFNMLNTKNC PSLKDKPKVI IIQACRGDSP GVVWFKDSVG
Target Information
Caspase-1 (CASP1) is a thiol protease that cleaves IL-1 beta between Asp and Ala, releasing the mature cytokine involved in inflammatory processes. CASP1 is essential for pathogen defense, activates sterol regulatory element binding proteins (SREBPs), and promotes apoptosis. Upon inflammasome activation during DNA virus infection, CASP1 controls antiviral immunity through cleavage and inactivation of CGAS.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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