Thermo Fisher Scientific KRT8 Monoclonal Antibody (OTI1B9), TrueMAB
KRT8 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 Immunocytochemistry에 적합. Human 및 Dog 반응성. Lyophilized 형태로 제공되며, PBS buffer와 trehalose 포함. 세포 구조 및 신호전달 연구용으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2500–1:5000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 91–381 of human CK8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Cytokeratin 8 is a type II keratin family member located on chromosome 12.
Type I and II keratins form intermediate filaments in epithelial cells.
Cytokeratin 8 typically pairs with keratin 18 to form filaments in simple epithelial cells.
It contributes to cellular structural integrity, signal transduction, and differentiation.
Mutations in this gene are associated with cryptogenic cirrhosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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