Thermo Fisher Scientific LYK5 Polyclonal Antibody
LYK5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Thermo Fisher Scientific LYK5 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human LYK5, amino acids 1–100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
LYK5, also known as STE20-related Adaptor Protein (STRAD) or FLJ90524, is mapped to locus 17q23.3. Members of the STE-20 like kinase family stimulate MAPK pathways by directly activating MAPKKK.
STRAD is a pseudokinase member of this family with a STE-20 like kinase domain but lacks key residues required for catalytic activity. It specifically binds LKB1 and regulates its tumor suppressor functions. STRAD acts as an upstream activator of LKB1 and anchors it in the cytoplasm, influencing its sub-cellular localization. The STRAD-LKB1 interaction leads to phosphorylation of STRAD and enhanced autophosphorylation of LKB1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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