Thermo Fisher Scientific Human Prosapip2 Synthetic Peptide
인간 Prosapip2 단백질의 C-말단 16개 아미노산에 해당하는 합성 펩타이드로, PA5-20814 항체의 차단 실험에 사용 가능. 바이러스 감염 신호전달 연구에 적합하며, TBK1 및 IKBKE 결합 연구용. 액상 형태로 PBS 버퍼에 보존.
- 카탈로그번호
- PEP0928
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human Prosapip2 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human Prosapip2.
PEP-0928 can be used as a blocking peptide with polyclonal antibody PA5-20814.
Target Information
Prosapip2 (TBKBP1) is essential for signal transduction during viral infection and plays a major role in the TNF/NF-kappa-B pathway. It acts as an adaptor protein that constitutively binds TBK1 (TANK-binding kinase) and IKBKE, contributing to antiviral innate immunity.
Prosapip2 is a 615 amino acid adaptor protein belonging to the fibrillar collagen family, consisting of trimers of identical alpha 1 chains linked by interchain disulfide bonds. It is ubiquitously expressed, with highest levels in ovary and neuronal systems. Prosapip2 binds TBK1 and assists activation of IRF3, regulating antiviral gene expression during infection. Recent studies show Prosapip2 interacts with ProSAP2/Shank3 and actin, suggesting a role as a linker between postsynaptic density and the cytoskeleton.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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