Thermo Fisher Scientific STIM1 Monoclonal Antibody (CDN3H4)
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
MA119451 | - | Thermo Fisher Scientific MA119451 STIM1 Monoclonal Antibody (CDN3H4) 100 ug pk | 재고문의 | pk | 621,000원 | - | 683,100원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1 µg/mL
View 8 publications 8 publications
Immunohistochemistry (IHC)
-
View 2 publications 2 publications
Immunohistochemistry (Paraffin) (IHC (P))
5 µg/mL
View 1 publication 1 publication
Immunohistochemistry (PFA fixed) (IHC (PFA))
-
View 1 publication 1 publication
Immunocytochemistry (ICC/IF)
Assay-dependent
Immunoprecipitation (IP)
Assay-dependent
Product Specifications
Species Reactivity
Human, Mouse, Rat
Published species
Human, Mouse
Host/Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
CDN3H4
Immunogen
Synthetic peptide corresponding to the C-terminal cytoplasmic part of STIM1 if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
STIM1,
uniProtId:
Q13586-1,
ncbiNodeId:
9606,
antigenRange:
685,
antigenLength:
685,
antigenImageFileName:
MA1-19451_STIM1_Q13586-1_House_mouse.svg,
antigenImageFileNamePDP:
MA1-19451_STIM1_Q13586-1_House_mouse_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4° C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2197884
Product Specific Information
This antibody reacts with a cytoplasmic epitope of human and rodent STIM1, a 84 kDa essential and conserved regulator of store-operated Ca2+ channel function.
Western Blot: Both reducing and non-reducing conditions; Immunocytochemistry: Methanol-acetone fixation.
Target Information
STIM1 (stromal interacting molecule; also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane. Following decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm. However, the precise mechanism of STIM1-Orai1 interaction has not been elucidated yet. Many questions also remain to be solved around STIM1 functional distribution. It turns out that STIM1 associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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