ELK Biotechnology SPB6 rabbit pAb
SPB6 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 인간 및 생쥐 시료에 반응하며, 세포질 내 단백질 검출에 활용됩니다. -20°C 보관 시 1년 안정적으로 유지됩니다.
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ELK Biotechnology SPB6 rabbit pAb
제품 설명
SPB6 rabbit pAb는 인간 SPB6 단백질을 인식하는 토끼 폴리클로날 항체입니다. 세린 프로테아제 억제제(serpin) 계열 단백질 연구에 사용되며, WB 및 ELISA 분석에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | SPB6 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 41 kD |
| Gene ID (Human) | 5269 |
| Human Swiss-Prot No. | P35237 |
| Cellular Localization | Cytoplasm |
| Species Reactivity | Human; Mouse |
Background
The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily and the ovalbumin (ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog is expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in protecting inner ear cells against lysosomal leakage during stress. Loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]
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