ELK Biotechnology RB33B rabbit pAb
RB33B rabbit pAb는 인간 및 마우스 시료에 반응하는 폴리클로날 항체로, WB와 ELISA에 적합합니다. 골지체 관련 단백질 인식에 특화되어 있으며, 단백질 수송 및 세포 내 소기관 연구에 유용합니다. -20°C에서 1년 보관 가능합니다.
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제품명
RB33B rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 100–180) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 25 kDa |
| GeneID (Human) | 83452 |
| Human Swiss-Prot No. | Q9H082 |
| Species Reactivity | Human; Mouse |
| Cellular Localization | Golgi apparatus membrane; Lipid-anchor; Golgi apparatus, cis-Golgi network. Under starvation conditions, punctate RAB33B-positive structures are often observed in the cytoplasm. |
Background
This gene encodes a small GTP-binding protein of the Rab GTPase family, whose members function in vesicle transport during protein secretion and endocytosis. Rab GTPases are active, membrane-associated proteins that recruit effector proteins in the GTP-bound state and inactive cytosolic proteins when in a GDP-bound state. The protein encoded by this gene is ubiquitously expressed and has been implicated in Golgi to endoplasmic reticulum cycling of Golgi enzymes. In addition, this protein regulates Golgi homeostasis and coordinates intra-Golgi retrograde trafficking. Allelic variants in this gene have been associated with Dyggve-Melchior-Clausen syndrome and Smith-McCort dysplasia 2, which are autosomal recessive spondyloepimetaphyseal dysplasias characterized by skeletal abnormalities. [provided by RefSeq, Sep 2016]
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