Thermo Fisher Scientific CLDN6 Monoclonal Antibody (OTI3E3), TrueMAB
인간 CLDN6 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 동결건조 형태로 제공되며, PBS 버퍼 내 트레할로스 포함. 연구용으로만 사용 가능하며, 재구성 및 결합 실험에 최적화되어 있습니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E3 |
| Immunogen | Full length human recombinant protein of human CLDN6 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Tight junctions are cell-to-cell adhesion structures in epithelial or endothelial sheets, forming continuous seals around cells and serving as barriers to solutes and water.
The CLDN6 gene encodes a component of these junction strands and is part of the claudin family.
The protein is an integral membrane protein and functions as an entry cofactor for hepatitis C virus.
Gene methylation may be associated with esophageal tumorigenesis.
CLDN6 is located adjacent to CLDN9 on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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